Trichomonal vaginitis. A 24-hr regimen of nimorazole compared with a 7-day regimen of metronidazole.

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Trichomonal vaginitis. A 24-hr regimen of nimorazole compared with a 7-day regimen of metronidazole.

A 24-hr regimen of nimorazole (1 g. orally at 12-hrly intervals for three doses) was compared with metronidazole (200 mg. three times daily for 7 days) in the treatment of trichomonal vaginitis. The two treatment schedules were given to alternate patients, pregnant women being excluded. One hundred cases were treated on each schedule; roughly one-fifth of the patients in each group defaulted. T...

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Nifuratel (Magmilor) was compared with metronidazole (Flagyl) in the treatment of trichomonal vaginitis by a randomized double-blind trial. Only 18 out of 47 patients (38%) treated with nifuratel were found to be cured, whereas 42 out of 49 patients (85%) treated with metronidazole were cured. Severe reactions, necessitating withdrawal of treatment, occurred in three patients treated with nifur...

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Trichomonal vaginitis treated with one dose of metronidazole.

Since its introduction in France, metronidazole (Flagyl) has become the standard treatment for trichomonal vaginitis (Durel, Roiron, Siboulet, and Borel, 1959). The course recommended at that time and continued ever since was 200 mg. three times daily for 7 days, giving a cure rate of 85 to 98 per cent. (Csonka, 1963; Evans and Catterall, 1970; Keighley, 1971). We have investigated the possibil...

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Nitrimidazine (Naxogin) compared with metronidazole (Flagyl) in the treatment of trichomonal vaginitis.

For more than 10 years very satisfactory results have been obtained in the treatment of trichomonal vaginitis using the standard 7-day course of metronidazole 200 mg. three times a day (Rodin, King, Nicol, and Barrow, 1960). In a recent trial it was shown that a 5-day course of 400 mg. twice daily produced equally satisfactory results, and was probably an easier regime from the patient's point ...

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Managing trichomonal vaginitis refractory to conventional treatment with metronidazole.

Three patients with vulvovaginitis caused by Trichomonas vaginalis, which was refractory to conventional treatment with metronidazole are described. The T vaginalis strain isolated from one patient was resistant to metronidazole (minimum inhibitory concentration (MIC) more than 100 mg/l) under aerobic conditions, although under anaerobic conditions it was as susceptible as a normal reference st...

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ژورنال

عنوان ژورنال: Sexually Transmitted Infections

سال: 1975

ISSN: 1368-4973

DOI: 10.1136/sti.51.1.54